Sagliker Syndrome in a Patient with Secondary Hyperparathyroidism and Chronic Renal Insufficiency: A Case Report

Authors

  • Narjess Ayati Nuclear Medicine Research Center, Mashhad University of Medical Science
  • Ramin Sadeghi Nuclear Medicine Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran
  • Sara Shakeri Nuclear Medicine Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:

Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated secondary hyperparathyroidism. It is described by severe skeletal deformities, high level of PTH in patients with chronic renal failure, and deformed face. This paper reports a 44-year-old male patient with the mentioned characteristics. In addition to the unique clinical features, high levels of ALP and PTH hormones encouraged us to search for syndrome-like a disease, which clinically and paraclinically matched the Sagliker syndrome.This case highlights the importance of clinicians’ attention for earlymonitoring and appropriate treatment as it is shown to be effective in preventing irreversible complications such as soft tissue and bone abnormalities and cardiovascular impairment in patients with Sagliker syndrome. Therefore, considering the syndrome isrecommended as one of the diagnostic hypothesis in young patients with renal insufficiency, secondary hyperparathyroidism, and skeletal deformities.

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Journal title

volume 6  issue 2

pages  167- 170

publication date 2018-06-01

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